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intercellular cell adhesion molecule 1 icam 1 antibody  (Proteintech)


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    Proteintech intercellular cell adhesion molecule 1 icam 1 antibody
    Intercellular Cell Adhesion Molecule 1 Icam 1 Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 2370 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/intercellular cell adhesion molecule 1 icam 1 antibody/product/Proteintech
    Average 96 stars, based on 2370 article reviews
    intercellular cell adhesion molecule 1 icam 1 antibody - by Bioz Stars, 2026-03
    96/100 stars

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    Figure 1. PCAF is highly expressed in coronary arteries of elderly patients and human atherosclerotic vessels. (A) All specimens were obtained from the proximal right coronary artery of the patient, and the expression of PCAF in human coronary arteries was detected by immunochemistry. The representative slides are shown; the scale bar is 1 mm, 2×. (B) The relationship between patient age and PCAF expression in human coronary arteries (n = 44). (C,D) The coronary intima produced “atherosclerotic plaque” as the criterion for judging atherosclerosis (AS). Western blot detects PCAF expression and aging-related protein (p53, p21, <t>p16,</t> <t>ICAM-1</t> and VCAM-1) levels in human coronary arteries (n = 3). (E,F) Nrf2 signal pathway related protein level was detected by western blot (n = 3). ** p < 0.01 vs. the control group.
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    Figure 1. PCAF is highly expressed in coronary arteries of elderly patients and human atherosclerotic vessels. (A) All specimens were obtained from the proximal right coronary artery of the patient, and the expression of PCAF in human coronary arteries was detected by immunochemistry. The representative slides are shown; the scale bar is 1 mm, 2×. (B) The relationship between patient age and PCAF expression in human coronary arteries (n = 44). (C,D) The coronary intima produced “atherosclerotic plaque” as the criterion for judging atherosclerosis (AS). Western blot detects PCAF expression and aging-related protein (p53, p21, <t>p16,</t> <t>ICAM-1</t> and VCAM-1) levels in human coronary arteries (n = 3). (E,F) Nrf2 signal pathway related protein level was detected by western blot (n = 3). ** p < 0.01 vs. the control group.
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    Figure 1. PCAF is highly expressed in coronary arteries of elderly patients and human atherosclerotic vessels. (A) All specimens were obtained from the proximal right coronary artery of the patient, and the expression of PCAF in human coronary arteries was detected by immunochemistry. The representative slides are shown; the scale bar is 1 mm, 2×. (B) The relationship between patient age and PCAF expression in human coronary arteries (n = 44). (C,D) The coronary intima produced “atherosclerotic plaque” as the criterion for judging atherosclerosis (AS). Western blot detects PCAF expression and aging-related protein (p53, p21, p16, ICAM-1 and VCAM-1) levels in human coronary arteries (n = 3). (E,F) Nrf2 signal pathway related protein level was detected by western blot (n = 3). ** p < 0.01 vs. the control group.

    Journal: International journal of molecular sciences

    Article Title: Downregulation of P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal Pathway Activation.

    doi: 10.3390/ijms232012574

    Figure Lengend Snippet: Figure 1. PCAF is highly expressed in coronary arteries of elderly patients and human atherosclerotic vessels. (A) All specimens were obtained from the proximal right coronary artery of the patient, and the expression of PCAF in human coronary arteries was detected by immunochemistry. The representative slides are shown; the scale bar is 1 mm, 2×. (B) The relationship between patient age and PCAF expression in human coronary arteries (n = 44). (C,D) The coronary intima produced “atherosclerotic plaque” as the criterion for judging atherosclerosis (AS). Western blot detects PCAF expression and aging-related protein (p53, p21, p16, ICAM-1 and VCAM-1) levels in human coronary arteries (n = 3). (E,F) Nrf2 signal pathway related protein level was detected by western blot (n = 3). ** p < 0.01 vs. the control group.

    Article Snippet: Antibodies against PCAF (#sc-13124), NAD(P)H quinone oxidoreductase-1 (#sc-376023), Cyclin-dependent kinase inhibitor 1A (p21) (#sc-6246), cyclin-dependent kinase inhibitor 2A (p16) (#sc-1661), intercellular cell adhesion molecule-1 (ICAM-1) (#sc-8439) and vascular cell adhesion molecule 1 (VCAM-1) (#sc-13160) were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA).

    Techniques: Expressing, Produced, Western Blot, Control

    Figure 2. Downregulation of PCAF inhibits AngII-induced senescence of ECs. (A,B) Western blot to determine the expression of PCAF in each group (n = 6). (C,D) β-galactosidase staining to detect senescence of ECs; Senescent VSMCs were marked in blue, the scale bar is 100 µm, 400× (n = 5). (E,F) p53, p21, p16, ICAM-1 and VCAM-1 protein expression (n = 6). (G) Detection of PCAF (green) and p21 (red) levels by immunofluorescence double staining; the scale bar is 100 µm, 400× (n = 3). ** p < 0.01 vs. the control group; # p < 0.05, ## p < 0.01 vs. the AngII induction with Ad-GFP group (AngII + Ad-GFP group).

    Journal: International journal of molecular sciences

    Article Title: Downregulation of P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal Pathway Activation.

    doi: 10.3390/ijms232012574

    Figure Lengend Snippet: Figure 2. Downregulation of PCAF inhibits AngII-induced senescence of ECs. (A,B) Western blot to determine the expression of PCAF in each group (n = 6). (C,D) β-galactosidase staining to detect senescence of ECs; Senescent VSMCs were marked in blue, the scale bar is 100 µm, 400× (n = 5). (E,F) p53, p21, p16, ICAM-1 and VCAM-1 protein expression (n = 6). (G) Detection of PCAF (green) and p21 (red) levels by immunofluorescence double staining; the scale bar is 100 µm, 400× (n = 3). ** p < 0.01 vs. the control group; # p < 0.05, ## p < 0.01 vs. the AngII induction with Ad-GFP group (AngII + Ad-GFP group).

    Article Snippet: Antibodies against PCAF (#sc-13124), NAD(P)H quinone oxidoreductase-1 (#sc-376023), Cyclin-dependent kinase inhibitor 1A (p21) (#sc-6246), cyclin-dependent kinase inhibitor 2A (p16) (#sc-1661), intercellular cell adhesion molecule-1 (ICAM-1) (#sc-8439) and vascular cell adhesion molecule 1 (VCAM-1) (#sc-13160) were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA).

    Techniques: Western Blot, Expressing, Staining, Double Staining, Control

    Figure 3. The PCAF inhibitor garcinol significantly attenuates the AngII-induced vascular ag- ing phenotype in mice. (A) H&E staining to observe the vascular structure—the scale bar is 100 µm, 100× (n = 3); immunofluorescence staining to detect the expression of PCAF (green) and p53 (red)—the scale bar is 100 µm, 200× (n = 3). (B) Detection of p16 (red) and p21 (green) expression in mice thoracic aorta by double immunofluorescence staining; the scale bar is 100 µm, 400× (n = 3). (C,D) Western blot detects the expression of PCAF, aging-related proteins (p53, p21, p16, VCAM-1 and ICAM-1) and Nrf2 signaling pathway proteins in mice thoracic aorta (n = 6). ** p < 0.01 vs. the Sham group; # p < 0.05, ## p < 0.01 vs. AngII group.

    Journal: International journal of molecular sciences

    Article Title: Downregulation of P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal Pathway Activation.

    doi: 10.3390/ijms232012574

    Figure Lengend Snippet: Figure 3. The PCAF inhibitor garcinol significantly attenuates the AngII-induced vascular ag- ing phenotype in mice. (A) H&E staining to observe the vascular structure—the scale bar is 100 µm, 100× (n = 3); immunofluorescence staining to detect the expression of PCAF (green) and p53 (red)—the scale bar is 100 µm, 200× (n = 3). (B) Detection of p16 (red) and p21 (green) expression in mice thoracic aorta by double immunofluorescence staining; the scale bar is 100 µm, 400× (n = 3). (C,D) Western blot detects the expression of PCAF, aging-related proteins (p53, p21, p16, VCAM-1 and ICAM-1) and Nrf2 signaling pathway proteins in mice thoracic aorta (n = 6). ** p < 0.01 vs. the Sham group; # p < 0.05, ## p < 0.01 vs. AngII group.

    Article Snippet: Antibodies against PCAF (#sc-13124), NAD(P)H quinone oxidoreductase-1 (#sc-376023), Cyclin-dependent kinase inhibitor 1A (p21) (#sc-6246), cyclin-dependent kinase inhibitor 2A (p16) (#sc-1661), intercellular cell adhesion molecule-1 (ICAM-1) (#sc-8439) and vascular cell adhesion molecule 1 (VCAM-1) (#sc-13160) were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA).

    Techniques: Staining, Expressing, Western Blot